Medical uses: Pridinol mesilate is used as a medication for the same indications with pridinol. It has muscle relaxant properties and is used for spasticity in neuromuscular diseases or to reduce stiffness associated with Parkinson's. Its efficacy in treating these conditions has been established by numerous studies and clinical uses of the drug.
This is why pridinol mesilato can be useful in the treatment of muscle spasticity, which many patients with disorders such as multiple sclerosis and cerebral palsy suffer from. Clinical studies have shown that pridinol mesilato can even produce up to a reduction of 50% in spasticity, greatly improving the range and quality of life for patients. Another example of this would be a three-month study from Neurology Reviews which showed significant muscle tone reduction and related physical function improvement in patients with spasticity receiving pridinol mesilato.
Pridinol mesilato is also usefull for treating symptoms of PD such as tremors, rigidity and bradykinesia. Studies have suggested that the drug can reduce Parkinsonian symptoms by 30% to 40%, providing symptom relief for patients with advanced stages of Parkinson's disease. In a double blind, placebo (PBO)-controlled trial of 150 subjects PL04 –abs 2 fewer than half of the participants completed; those that were normal weight age- range treated with pridinol mesilato reported significantly more improved control of tremor severity compared to improvement in motor function.
In addition to spasticity and the Parkinsonian symptom syndrome, pridinol mesylate is also used in other forms of movement disorder such as dystonia. A study was published in the Journal Movement Disorders that showed treatment with pridinol mesilato produced a reduction >40% of dystonic movements in patients, emphasizing its beneficial effects on this difficult condition. Its mechanism of action is thought to involve modulation of neurotransmitter function in the central nervous system resulting in a reduction in frequency, and severity abnormal muscle contractions.
Based on Dr. Linda Martinez, a professional in the area of Neurology: “Pridinol mesilato is key to treating many patients with neuromuscular and motility problems”. This is a critical feature for the therapeutic use of this medication -- it demonstrates that it can be designed to target motor symptoms with specificity.
The therapeutic potential of pridinol mesilato can be exploited in post-stroke rehabilitation and other applications. Pridinol mesilato is an appropriate pharmacological choice to treat spasticity and loss of motor activity in the rehabilitation management of patients after a stroke. Clinical observations show that this medication seems to improve motor recovery and functional outcomes in rehabilitation.
Learn more about where you can use Pridinol Mesilato and the Benefits of join here. These different utilizations of pridinol mesilato for the treatment of muscle spasticity, Parkinsonian manifestations and dystonia indicate its high value to meet patient demands in a diverse range neurological as well out musculoskeletal diseases.